The Colleen Giblin Research Laboratories for Pediatric Neurology

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Introduction

research laboratoryThe Colleen Giblin Research Laboratories for Pediatric Neurology, a unique training and scientific resource, and the Giblin Foundation, were established in 1985 by the Giblin family in memory of Colleen, their daughter, who succumbed to a brain tumor.

Today, the Laboratories serve as a forum where physicians and scientists from practically all areas of the world conduct research on the molecular genetics, diagnosis and treatment of diseases of the developing human brain. Researchers are encouraged to tackle virtually all areas of neurological disease using the latest advances in molecular and cellular biology and genetics. Former trainees and associates have developed similar research enterprises in the U.S. and other countries modeled after the Giblin Laboratories.The annual Colleen Giblin Award and Lecture series provide additional opportunities for interaction with prestigious visiting researchers of international renown.

Research is supported by the Colleen Giblin Foundation, the National Institutes of Neurological Disorders and Stroke, patients, families and many generous benefactors without whose help our endeavors could not be possible.

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Research Highlights

  • Glucose transporter deficiency syndrome
  • Spinal Muscular Atrophy
  • MELAS (mitochondrial encephalopathy, lactic acidosis and stroke-like episodes) therapy
  • MELAS natural history
  • Sickle cell disease encephalopathy
  • Novel chemotherapeutic agents for brain tumors
  • Ion channel diseases
  • Pyruvate dehydrogenase deficiency
  • Pyruvate carboxylase deficiency
  • Transgenic animal models of human disease
  • Metabolic imaging of the developing human brain
  • Gene induction therapies
  • Molecular and genetic diagnosis
  • Newborn neuromuscular diseases
  • Reye syndrome
  • Carnitine deficiency syndromes
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